circRNA basic information
circBase ID: hsa_circ_0000218
Name: hsa_circ_DCLRE1C
Synonym: -
Host Gene: hsa-miR-139-3p
 
 
 
Disease basic information
DO ID:
 2876
DO name: laryngeal squamous cell carcinoma
Disease details: laryngeal squamous cell carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: LSCC cell line (SNU46, SNU899), normal human hypopharyngeal cells (NHPs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Smad3
Associated microRNA: hsa-miR-139-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0000218 inhibition inhibited the growth of LSCC by targeting miR-139-3p/Smad3 axis.

Other information
Title:

Circ_0000218 plays a carcinogenic role in laryngeal cancer through regulating microRNA-139-3p/Smad3 axis.

Journal: Pathol Res Pract
Published: 2020/8/23
PubMed ID: 32825967