circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-508-3p
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human ccRCC cell lines (A498, 786-O, 769-P), a human renal proximal tubular epithelial HK2 cell line (HRPTEpiC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CXCL13
Associated microRNA: hsa-miR-508-3p
Biological function: Promotes Clear Cell Renal Cell Carcinoma (ccRCC) Cells Proliferation and Metastasis
Molecular mechanism: via Altering of hsa-miR-508-3p/CXCL13 Signal
Survival: -
Supported No.:
 1
Description:

circHIPK3 promoted ccRCC cell proliferation and metastasis by altering miR-5083p/CXCL13 signaling. The present findings might provide a novel target for the molecular treatment of ccRCC.
Other information
Title:

CircHIPK3 Promotes Clear Cell Renal Cell Carcinoma (ccRCC) Cells Proliferation and Metastasis via Altering of miR-508-3p/CXCL13 Signal.

Journal: Onco Targets Ther
Published: 2020/8/22
PubMed ID: 32821115