circRNA basic information
circBase ID: -
Name: hsa_circ_Foxp1
Synonym: -
Host Gene: hsa-miR-22, hsa-miR-150-3p
 
 
 
Disease basic information
DO ID:
 2152
DO name: ovary epithelial cancer
Disease details: epithelial ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: EOC cell lines (COC1, OVCAR3, SKOV3, SKOV3/DDP), normal human ovarian epithelial cells (IOSE-80)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-22, hsa-miR-150-3p
Biological function: promote cell proliferation and confer DDP resistance
Molecular mechanism: through hsa-miR-22 and hsa-miR-150-3p
Survival: -
Supported No.:
 1
Description:

circFoxp1 is an oncogene in EOC cells and can confer DDP resistance to EOC cells. Circulating exosomal circFoxp1 can be used as a biomarker and potential therapeutic target for EOC.
Other information
Title:

Circulating exosomal circFoxp1 confers cisplatin resistance in epithelial ovarian cancer cells.

Journal: J Gynecol Oncol
Published: 2020/8/19
PubMed ID: 32808501