circRNA basic information
circBase ID: -
Name: hsa_circ_TADA2A
Synonym: -
Host Gene: hsa-miR-374a-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human CRC cell lines (HCT116, SW620, LoVo, SW480), normal human colon epithelial cell line (NCM460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: KLF14
Associated microRNA: hsa-miR-374a-3p
Biological function: inhibit the glycolysis and cell cycle and potentiate the apoptosis of CRC cells
Molecular mechanism: via hsa-miR-374a-3p/KLF14 axis
Survival: -
Supported No.:
 3
Description:

CircTADA2A functioned as a tumor suppressor in CRC to inhibit the glycolysis and cell cycle and potentiate the apoptosis of CRC cells via miR-374a-3p/KLF14 axis.
Other information
Title:

CircTADA2A suppresses the progression of colorectal cancer via miR-374a-3p/KLF14 axis.

Journal: J Exp Clin Cancer Res
Published: 2020/8/18
PubMed ID: 32799891