circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_101141
Host Gene: hsa-miR-1297
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (MHCC97 H, HCCLM3, SK-HEP-1, Hep3B, Huh7), normal human liver cell line (LO2), HEK293 cell line
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ROCK1
Associated microRNA: hsa-miR-1297
Biological function: downregulation of circ_101141 dramatically inhibited cell proliferation, migration, and invasion in HCC cells
Molecular mechanism: regulating hsa-miR-1297/ROCK1 pathway
Survival: -
Supported No.:
1
Description:

circRNA circ_101141 acted as a ceRNA to facilitate tumorigenesis of HCC by regulating miR-1297/ROCK1 pathway.

Other information
Title:

Circular RNA hsa_Circ_101141 as a Competing Endogenous RNA Facilitates Tumorigenesis of Hepatocellular Carcinoma by Regulating miR-1297/ROCK1 Pathway.

Journal: Cell Transplant
Published: 2020/8/14
PubMed ID: 32787581