circRNA basic information
circBase ID: hsa_circ_0008193
Name: -
Synonym: circ_0008193
Host Gene: hsa-miR-1180-3p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human LUAD cell lines (A549, H1975), normal human lung epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TRIM62
Associated microRNA: hsa-miR-1180-3p
Biological function: inhibited cell viability, glucose uptake, lactate production, migration, and invasion
Molecular mechanism: regulation of the hsa-miR-1180-3p/TRIM62 axis
Survival: better
Supported No.:
 1
Description:

Upregulating circ_0008193 inhibited LUAD cell proliferation, migration, invasion, and Warburg effect under hypoxia in vitro and in vivo through regulation of the miR-1180-3p/TRIM62 axis.
Other information
Title:

A Regulatory Axis of circ_0008193/miR-1180-3p/TRIM62 Suppresses Proliferation, Migration, Invasion, and Warburg Effect in Lung Adenocarcinoma Cells Under Hypoxia.

Journal: Med Sci Monit
Published: 2020/8/13
PubMed ID: 32782238