circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-637
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U2OS, SW1353 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STAT3
Associated microRNA: hsa-miR-637
Biological function: promote the migration, invasion, and growth of OS cells
Molecular mechanism: circHIPK3/hsa-miR-637/STAT3 pathway
Survival: -
Supported No.:
 4
Description:

our research uncovered an important role of the circHIPK3/miR-637/STAT3 pathway in the migration and invasion of OS cells and suggested that circHIPK3 may be a prognostic marker and a promising therapeutic target for OS.
Other information
Title:

Circular RNA circHIPK3 Promotes Cell Metastasis through miR-637/STAT3 Axis in Osteosarcoma.

Journal: Biomed Res Int
Published: 2020/8/11
PubMed ID: 32775413