circRNA basic information
circBase ID: hsa_circ_0067934
Name: hsa_circ_PRKCI
Synonym: -
Host Gene: hsa-miR-1182
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal bronchial epithelial cell line (16HBE), NSCLC cell lines (H358, H23)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF8
Associated microRNA: hsa-miR-1182
Biological function: Circ_0067934 knockdown blocked proliferation, migration, invasion and EMT and induced apoptosis in NSCLC cells.
Molecular mechanism: sponging hsa-miR-1182
Survival: -
Supported No.:
 3
Description:

Circ_0067934 acted as a competing endogenous RNA to facilitate NSCLC progression by regulating the miR-1182/KLF8 axis and activating Wnt/beta-catenin pathway.
Other information
Title:

Circ_0067934 promotes non-small cell lung cancer development by regulating miR-1182/KLF8 axis and activating Wnt/beta-catenin pathway.

Journal: Biomed Pharmacother
Published: 2020/8/10
PubMed ID: 32768951