circRNA basic information
circBase ID: hsa_circ_0016760
Name: hsa_circ_SNAP47
Synonym: -
Host Gene: hsa-miR-577
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: NSCLC cell lines (A549, H1299, H1975)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZBTB7A
Associated microRNA: hsa-miR-577
Biological function: Circ_0016760 exhaustion curbed the colony formation, migration, invasion, and ECAR of NSCLC cells in vitro and impeded tumor growth in vivo
Molecular mechanism: through regulation of the hsa-miR-577/ZBTB7A axis
Survival: -
Supported No.:
 6
Description:

Circ_0016760 and ZBTB7A were upregulated and miR-577 was downregulated in NSCLC tissues and cells. Circ_0016760 exhaustion curbed the colony formation, migration, invasion, and ECAR of NSCLC cells in vitro and impeded tumor growth in vivo.Circ_0016760 silencing impeded NSCLC advancement through regulation of the miR-577/ZBTB7A axis.
Other information
Title:

Circular RNA Circ_0016760 Modulates Non-Small-Cell Lung Cancer Growth Through the miR-577/ZBTB7A Axis.

Journal: Cancer Manag Res
Published: 2020/8/6
PubMed ID: 32753969