circRNA basic information
circBase ID: -
Name: hsa_circ_FAT1
Synonym: -
Host Gene: hsa-miR-181b
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SW1353, U2OS, MG-63, normal cell hFOB 1.19
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HK2
Associated microRNA: hsa-miR-181b
Biological function: circFAT1(e2) depletion significantly suppressed the proliferation and reduced migration
Molecular mechanism: circFAT1(e2)/hsa-miR-181b/HK2 axis
Survival: -
Supported No.:
 2
Description:

circFAT1(e2) exerted oncogenic roles in OS and suggested the circFAT1(e2)/miR-181b/HK2 axis might be a potential therapeutic target.
Other information
Title:

Circular RNA circFAT1(e2) Promotes Osteosarcoma Progression and Metastasis by Sponging miR-181b and Regulating HK2 Expression.

Journal: Biomed Res Int
Published: 2020/8/1
PubMed ID: 32733938