circRNA basic information
circBase ID: -
Name: hsa_circ_ITCH
Synonym: cir-ITCH, circ-ITCH
Host Gene: hsa-miR-106a
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A2780, OVCAR3, ISOE80
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: CDH1
Associated microRNA: hsa-miR-106a
Biological function: suppressed proliferation, invasion, glycolysis, and promoted apoptosis
Molecular mechanism: modulating the hsa-miR-106a/CDH1 axis
Survival: better
Supported No.:
 4
Description:

Circ-ITCH suppressed proliferation, invasion, glycolysis, and promoted apoptosis of ovarian cancer cells by modulating the miR-106a/CDH1 axis.
Other information
Title:

Circular RNA ITCH suppresses proliferation, invasion, and glycolysis of ovarian cancer cells by up-regulating CDH1 via sponging miR-106a.

Journal: Cancer Cell Int
Published: 2020/7/28
PubMed ID: 32714095