circRNA basic information
circBase ID: hsa_circ_0005909
Name: hsa_circ_XPR1
Synonym: -
Host Gene: hsa-miR-936
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal osteoblast (hFOB1.19), OS cell lines (HOS, U2OS, SAOS-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB1
Associated microRNA: hsa-miR-936
Biological function: Silencing of circITGA7 inhibits metastasis and proliferation
Molecular mechanism: acts as hsa-miR-198 competitive endogenous RNA (ceRNA) to regulate FGFR1 expression
Survival: poor
Supported No.:
 2
Description:

Circ_0005909 inhibition impeded the progression of OS via downregulating HMGB1 via sponging miR-936.
Other information
Title:

Circular RNA hsa_circ_0005909 modulates osteosarcoma progression via the miR-936/HMGB1 axis.

Journal: Cancer Cell Int
Published: 2020/7/21
PubMed ID: 32684842