circRNA basic information
circBase ID: -
Name: hsa_circ_MMP11
Synonym: -
Host Gene: hsa-miR-1204
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human mammary epithelial cell lines (HBL-100), breast cancer cell lines (MCF7, T47D, MDA-MB-453, MDA-MB-231, MDA-MB-468, Hs578T)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MMP11
Associated microRNA: hsa-miR-1204
Biological function: The inhibition of circMMP11 suppressed cell proliferation and migration of BC
Molecular mechanism: regulating hsa-miR-1204
Survival: -
Supported No.:
 4
Description:

The circMMP11/miR-1204/MMP11 axis regulates breast cancer progression via a competitive endogenous RNA (ceRNA) mechanism. CircMMP11 may serve as a potential therapeutic target in BC.
Other information
Title:

CircMMP11 acts as a ce-circRNA in breast cancer progression by regulating miR-1204.

Journal: Am J Transl Res
Published: 2020/7/14
PubMed ID: 32655792