circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-421
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human astrocytes (NHA), glioma cell lines (A172, U251)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ZIC5
Associated microRNA: hsa-miR-421
Biological function: Facilitates Tumor Progression and Temozolomide Resistance
Molecular mechanism: Regulating hsa-miR-421/ZIC5 Axis
Survival: -
Supported No.:
 7
Description:

Exosomal circ-HIPK3 could promote cell progression and TMZ resistance by regulating miR-421/ZIC5 axis in TMZ-resistant glioma.
Other information
Title:

Exosomal circ-HIPK3 Facilitates Tumor Progression and Temozolomide Resistance by Regulating miR-421/ZIC5 Axis in Glioma.

Journal: Cancer Biother Radiopharm
Published: 2020/7/10
PubMed ID: 32644821