circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_100859
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human colon cancer cell lines (HCT116, HT29, SW480), normal human intestinal epithelial cell lines (Lovo)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF-1alpha
Associated microRNA: hsa-miR-217
Biological function: promoted cell proliferation and inhibited cell apoptosis
Molecular mechanism: sponging the hsa-miR-217-HIF-1alpha pathway
Survival: poor
Supported No.:
 1
Description:

the circRNA_100859-miR-217-HIF-1alpha axis may serve as a novel diagnostic and prognostic biomarker for patients with colon cancer.
Other information
Title:

circRNA_100859 functions as an oncogene in colon cancer by sponging the miR-217-HIF-1alpha pathway.

Journal: Aging (Albany NY)
Published: 2020/7/10
PubMed ID: 32644049