circRNA basic information
circBase ID: -
Name: rno_circ_PAN3
Synonym: -
Host Gene: rno-miR-221
 
 
 
Disease basic information
DO ID:
 1287
DO name: cardiovascular system disease
Disease details: cardiovascular disease
Species: rat
Species details: rat
Sample type: tissue, cell line
Sample type details: cardiac fibroblasts (CFs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FoxO3/ATG7
Associated microRNA: rno-miR-221
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circPAN3 exhibited profibrotic effects during autophagy-mediated cardiac fibrosis via miR-221/FoxO3/ATG7 axis, which may serve as potential biomarkers for cardiac fibrosis therapeutics.
Other information
Title:

circPAN3 exerts a profibrotic role via sponging miR-221 through FoxO3/ATG7-activated autophagy in a rat model of myocardial infarction.

Journal: Life Sci
Published: 2020/7/7
PubMed ID: 32629000