circRNA basic information
circBase ID: hsa_circ_0070934
Name: hsa_circ_LARP1B
Synonym: -
Host Gene: hsa-miR-1236-3p
 
 
 
Disease basic information
DO ID:
 3151
DO name: skin squamous cell carcinoma
Disease details: cutaneous squamous cell carcinoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: human embryonic cell line (293T), human keratinocyte cell line (HaCaT), CSCC cell lines (A431, HSC-5, SCC13, SCL-1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXB7
Associated microRNA: hsa-miR-1236-3p
Biological function: Knockdown of circ_0070934 inhibited the invasive and proliferative potential of CSCC cells and promoted apoptosis both in vivo and in vitro
Molecular mechanism: regulate HOXB7 expression by sponging miR_1236_3p
Survival: -
Supported No.:
 5
Description:

the effects of the circ_0070934/miR_1236_3p/HOXB7 regulatory axis on CSCC and provided a novel insight for the pathogenesis of CSCC.
Other information
Title:

CircRNA hsa_circ_0070934 functions as a competitive endogenous RNA to regulate HOXB7 expression by sponging miR_1236_3p in cutaneous squamous cell carcinoma.

Journal: Int J Oncol
Published: 2020/7/7
PubMed ID: 32626939