circRNA basic information
circBase ID: hsa_circ_0080145
Name: hsa_circ_TNS3
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 8552
DO name: chronic myeloid leukemia
Disease details: chronic myeloid leukemia
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: human CML cell lines (KCL22, KG-1, K562, KU812)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PPFIA1
Associated microRNA: hsa-miR-326
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

circ_0080145 contributes to IM resistance via modulating miR-326/PPFIA1 axis, which might provide a novel avenue for CML therapy.
Other information
Title:

circ_0080145 Enhances Imatinib Resistance of Chronic Myeloid Leukemia by Regulating miR-326/PPFIA1 Axis.

Journal: Cancer Biother Radiopharm
Published: 2020/7/1
PubMed ID: 32598170