circRNA basic information
circBase ID: -
Name: hsa_circ_ABCB10
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 1993
DO name: rectum cancer
Disease details: rectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human rectal mucosa epithelium cell line (FHC), rectal cancer cell lines (SW837, HR-8348)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCL5
Associated microRNA: hsa-miR-326
Biological function: The knockdown of circABCB10 promoted rectal cancer cell ferroptosis and apoptosis in vitro as well as inhibited tumor growth in vivo
Molecular mechanism: served as a sponge of hsa-miR-326 to regulate the CCL5 expression
Survival: -
Supported No.:
 1
Description:

CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer.
Other information
Title:

CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer.

Journal: Neoplasma
Published: 2020/6/23
PubMed ID: 32567935