circRNA basic information
circBase ID: hsa_circ_0007841
Name: hsa_circ_SEC61A1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
9538
DO name: multiple myeloma
Disease details: multiple myeloma
Species: human
Species details: human
Sample type: cell line
Sample type details: THP-1, KM3, U266, RPMI-8226
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ABCG2
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
5
Description:

Our data collectively suggest a new model in which hsa_circ_0007841 promotes acquired chemotherapy resistance by upregulating ATP-binding cassette transporters G2 providing a novel molecular basis of chemotherapy in multiple myeloma cancer.

Other information
Title:

Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2.

Journal: Technol Cancer Res Treat
Published: 2020/6/20
PubMed ID: 32552614