circRNA basic information
circBase ID: hsa_circ_0008433
Name: hsa_circ_PDE4B
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 288
DO name: endometriosis of uterus
Disease details: endometriosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: The hsa_circ_0008433 knockdown inhibited endometrial stromal cell proliferation, migration, colony formation, and angiopoiesis; promoted cell apoptosis
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

The hsa_circ_0008433 knockdown inhibited endometrial stromal cell proliferation, migration, colony formation, and angiopoiesis; promoted cell apoptosis; and downregulated Ki67 and PCNA expression levels. Moreover, the hsa_circ_0008433 knockdown increased Bax and E-CAD expression and decreased Bcl2, CDKN1B, and CyclinD1 levels.
Other information
Title:

Upregulated Circular RNA hsa_circ_0008433 Regulates Pathogenesis in Endometriosis Via miRNA.

Journal: Reprod Sci
Published: 2020/6/18
PubMed ID: 32548806