circRNA basic information
circBase ID: -
Name: hsa_circ_FMN2
Synonym: -
Host Gene: hsa-miR-1238
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human PCa cell line (PC-3, DU145, VCaP, LNCaP), human normal prostate epithelial cell line (RWPE-1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: LHX2
Associated microRNA: hsa-miR-1238
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circFMN2 acts as a competing endogenous RNA (ceRNA) for miR-1238 to regulate LIM-homeobox gene 2 (LHX2) expression. circFMN2 regulates the miR-1238/LHX2 axis to promote PCa progression.
Other information
Title:

circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells.

Journal: Mol Ther Nucleic Acids
Published: 2020/6/12
PubMed ID: 32526477