circRNA basic information
circBase ID: -
Name: hsa_circ_BPTF
Synonym: CircBPTF
Host Gene: hsa-miR-384
 
 
 
Disease basic information
DO ID:
 4194
DO name: glucose metabolism disease
Disease details: high glucose-induced inflammatory injuries and oxidative stress
Species: human
Species details: human
Sample type: cell line
Sample type details: HUVEC
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LIN28B
Associated microRNA: hsa-miR-384
Biological function: CircBPTF knockdown increased cell viability and suppressed cell apoptosis, the release of proinflammatory cytokines and oxidative stress in HG-induced HUVECs
Molecular mechanism: circBPTF positively regulated LIN28B expression via targeting miR-384
Survival: -
Supported No.:
 1
Description:

CircBPTF knockdown protected against HG-induced inflammatory injuries and oxidative stress by mediating the miR-384/LIN28B axis in HUVECs
Other information
Title:

CircBPTF knockdown ameliorates high glucose-induced inflammatory injuries and oxidative stress by targeting the miR-384/LIN28B axis in human umbilical vein endothelial cells.

Journal: Mol Cell Biochem
Published: 2020/6/12
PubMed ID: 32524321