circRNA basic information
circBase ID: hsa_circ_0109320
Name: hsa_circ_ZNF91
Synonym: -
Host Gene: hsa-miR-595
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human airway epithelial cells (16HBE), NSCLC cell lines (H358, H1299, H1581, A549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F7
Associated microRNA: hsa-miR-595
Biological function: the suppression of circ_0109320 attenuates NSCLC cell proliferation and invasion and enhances apoptosis
Molecular mechanism: through the hsa-miR-595/E2F7 pathway
Survival: poor
Supported No.:
 2
Description:

Circ_0109320/miR-595/E2F2 axis may exert a pivotal role in the pathological mechanism of NSCLC progression, and it has potential application in the future treatment of NSCLC.
Other information
Title:

Suppression of Circular RNA Hsa_circ_0109320 Attenuates Non-Small Cell Lung Cancer Progression via MiR-595/E2F7 Axis.

Journal: Med Sci Monit
Published: 2020/6/9
PubMed ID: 32508344