circRNA basic information
circBase ID: hsa_circ_0078607
Name: hsa_circ_SLC22A3
Synonym: -
Host Gene: hsa-miR-518a-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human ovarian cancer cell lines (SKOV3, A2780)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: Fas
Associated microRNA: hsa-miR-518a-5p
Biological function: suppressed proliferation and promoted apoptosis
Molecular mechanism: sponging oncogenic hsa-miR-518a-5p to induce Fas expression
Survival: -
Supported No.:
 4
Description:

that circ_0078607 suppressed ovarian cancer progression by sponging oncogenic miR-518a-5p to induce Fas expression, which may provide new therapeutic approach for ovarian cancer.
Other information
Title:

Circular RNA hsa_circ_0078607 suppresses ovarian cancer progression by regulating miR-518a-5p/Fas signaling pathway.

Journal: J Ovarian Res
Published: 2020/6/7
PubMed ID: 32503653