circRNA basic information
circBase ID: hsa_circ_0081108
Name: hsa_circ_COL1A2
Synonym: -
Host Gene: hsa-miR-29b
 
 
 
Disease basic information
DO ID:
 8947
DO name: diabetic retinopathy
Disease details: diabetic retinopathy
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VEGF
Associated microRNA: hsa-miR-29b
Biological function: promotes angiogenesis
Molecular mechanism: regulating hsa-miR-29b/VEGF axis
Survival: -
Supported No.:
 4
Description:

circCOL1A2 facilities angiogenesis during the pathological progression of DR via regulating miR-29b/VEGF axis, suggesting that targeting circCOL1A2 may be a potential treatment for DR.
Other information
Title:

Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy.

Journal: Life Sci
Published: 2020/6/5
PubMed ID: 32497630