circRNA basic information
circBase ID: -
Name: hsa_circ_LPAR3
Synonym: -
Host Gene: hsa-miR-198
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ESCC cell lines (ECA109, TE_13, Kyse150, Kyse450, Kyse510), normal esophageal epithelial cells (HET_1A)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MET
Associated microRNA: hsa-miR-198
Biological function: promote the migration, invasion, and metastasis
Molecular mechanism: regulate the hsa-miR-198-MET signal axis
Survival: poor
Supported No.:
 1
Description:

Circular RNA LPAR3 can regulate the miR-198-MET signal axis to promote the migration, invasion, and metastasis of esophageal cancer cells, which can thereby serve as a potential diagnostic and therapeutic target of esophageal cancer.
Other information
Title:

Circular RNA LPAR3 sponges microRNA-198 to facilitate esophageal cancer migration, invasion, and metastasis.

Journal: Cancer Sci
Published: 2020/6/5
PubMed ID: 32495982