circRNA basic information
circBase ID: hsa_circ_0061140
Name: hsa_circ_C20orf11
Synonym: -
Host Gene: hsa-miR-1236
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Six human BCa cells (T24, 253j, 5637, J82, RT4, UMUC3), one human bladder epithelial immortalized cell (SV-HUC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1236
Biological function: silencing microRNA-1236 reversed the impact of the knockdown of circ_0061140 on the ability of BCa cells to proliferate and invade
Molecular mechanism: adsorbing microRNA-1236
Survival: poor
Supported No.:
 1
Description:

Circ_0061140 level was found remarkably elevated in BCa tissues, as well as in cell lines, which was closely relevant to the incidence of lymph node or distant metastasis of BCa patients. In addition, circ_0061140 may enhance the proliferation rate and invasion ability of BCa cells through the modulation of microRNA-1236.
Other information
Title:

Circ_0061140 promotes metastasis of bladder cancer through adsorbing microRNA-1236.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/6/5
PubMed ID: 32495864