circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_101237
Host Gene: hsa-miR-490-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human embryonic lung fibroblasts (MRC-5) cells, NSCLC cell lines (A549 cells, H1299 cells)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: MAPK1
Associated microRNA: hsa-miR-490-3p
Biological function: significantly promoting NSCLC cell lines proliferation, migration, and invasion
Molecular mechanism: sponged hsa-miR-490-3p to enhance MAPK1 expression
Survival: poor
Supported No.:
 1
Description:

hsa_circRNA_101237 promoted the expression of MAPK1 via miRNA-490-3p sponge, thus affecting the NSCLC as an important onco-circRNA.
Other information
Title:

CircRNA_101237 promotes NSCLC progression via the miRNA-490-3p/MAPK1 axis.

Journal: Sci Rep
Published: 2020/6/5
PubMed ID: 32494004