circRNA basic information
circBase ID: -
Name: hsa_circ_FARSA
Synonym: -
Host Gene: hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human fetal colon epithelial cell line (FHC), CRC cell lines (LS174T, RKO, HT29, HCT116, SW480)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LASP1
Associated microRNA: hsa-miR-330-5p
Biological function: Knockdown of circ-FARSA inhibited the proliferation, migration, and invasion of CRC cells in vitro
Molecular mechanism: regulating the hsa-miR-330-5p/LASP1 axis
Survival: poor
Supported No.:
 1
Description:

Silencing of circ-FARSA restricted the growth of CRC through regulating the miR-330-5p/LASP1 axis, providing a novel regulatory mechanism for CRC tumorigenesis.
Other information
Title:

Knockdown of circular RNA circ-FARSA restricts colorectal cancer cell growth through regulation of miR-330-5p/LASP1 axis.

Journal: Arch Biochem Biophys
Published: 2020/6/1
PubMed ID: 32473899