circRNA basic information
circBase ID: hsa_circ_0002375
Name: hsa_circ_KITLG
Synonym: -
Host Gene: hsa-miR-3198
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NPC cell lines (HNE1, HNE2, HNE3, CNE1, CNE2, 5-8F, HK1)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-3198
Biological function: Silencing of circKITLG inhibited NPC cell proliferation, migration, and invasion in vitro
Molecular mechanism: sponging up hsa-miR-3198
Survival: -
Supported No.:
 1
Description:

CircRNA-miRNA-target gene network analysis revealed a potential mechanism that hsa_circ_0002375 (circKITLG) may be involved in NPC through sponging up miR-3198 and interfering with its downstream targets. Silencing of circKITLG inhibited NPC cell proliferation, migration, and invasion in vitro.

Other information
Title:

Circular RNA Expression Profiles in Nasopharyngeal Carcinoma by Sequence Analysis.

Journal: Front Oncol
Published: 2020/5/20
PubMed ID: 32426279