circRNA basic information
circBase ID: -
Name: hsa_circ_NRIP1
Synonym: -
Host Gene: hsa-miR-138-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human normal gastric cell line (GES-1), GC cell lines (SGC-7901, AGS, MKN-45, MGC-803, HGC-27, BGC-823)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-138-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 6
Description:

circNRIP1 functioned as a miR-138-5p sponge to enhance hypoxia-induced resistance to 5-FU through modulation of HIF-1alpha-dependent glycolysis, which provides a novel potential approach to overcome hypoxia-induced 5-FU resistance in GC.
Other information
Title:

Circular RNA circNRIP1 Sponges microRNA-138-5p to Maintain Hypoxia-Induced Resistance to 5-Fluorouracil Through HIF-1alpha-Dependent Glucose Metabolism in Gastric Carcinoma.

Journal: Cancer Manag Res
Published: 2020/5/20
PubMed ID: 32425596