circRNA basic information
circBase ID: hsa_circ_0025033
Name: -
Synonym: Circ_0025033
Host Gene: hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: OC cells (A2780, SKOV3), human normal ovarian epithelial cells (HOSE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLK4
Associated microRNA: hsa-miR-330-5p
Biological function: Circ_0025033 knockdown inhibited OC cell viability, migration, invasion and EMT while expedited apoptosis.
Molecular mechanism: via the hsa-miR-330-5p/KLK4 axis
Survival: -
Supported No.:
 4
Description:

This study demonstrated that circ_0025033 contributed to the progression of OC via the miR-330-5p/KLK4 axis and might be a candidate target in the identification and treatment of OC.
Other information
Title:

Circular RNA Circ_0025033 Promotes the Evolvement of Ovarian Cancer Through the Regulation of miR-330-5p/KLK4 Axis.

Journal: Cancer Manag Res
Published: 2020/5/20
PubMed ID: 32425594