circRNA basic information
circBase ID: hsa_circ_0005615
Name: hsa_circ_NFATC3
Synonym: -
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human CRC cells (HCT 116, LoVo, HT-29, SW480)
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
UP
Associated gene: TNKS
Associated microRNA: hsa-miR-149-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 3
Description:

circ5615 exerted oncogenic function as competing endogenous RNA (ceRNA) of miR-149-5p to release TNKS and activated Wnt/beta-catenin pathway.
Other information
Title:

circ5615 functions as a ceRNA to promote colorectal cancer progression by upregulating TNKS.

Journal: Cell Death Dis
Published: 2020/5/13
PubMed ID: 32393760