circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_103809
Host Gene: -
 
 
 
Disease basic information
DO ID:
0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: sum-1315, MCF7, MDA-MB-231, MCF10A
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: The expression of circ_103809 in breast cancer was overexpressed. circ_103809 was proved to promote cell proliferation in breast cancer progression. In addition, circ_103809 was also involved in repressing cell apoptosis and accelerating cell cycle progression in vitro
Molecular mechanism: regulating PI3K/AKT signaling
Survival: -
Supported No.:
1
Description:

hsa_circ_103809 was highly expressed in breast cancer tissues and cells, and may play an oncogene role in the development of breast cancer, and is expected to become a new target for breast cancer therapy.

Other information
Title:

circ_103809 promotes breast cancer progression by regulating the PI3K/AKT signaling pathway.

Journal: Oncol Lett
Published: 2020/5/10
PubMed ID: 32382325