circRNA basic information
circBase ID: -
Name: hsa_circ_WHSC1
Synonym: circWHSC1
Host Gene: hsa-miR-646
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human endometrial cancer cell lines (HEC_1B, Ishikawa)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NPM1
Associated microRNA: hsa-miR-646
Biological function: promoted the proliferation, migration and invasion of endometrial cancer cells and decreased apoptosis
Molecular mechanism: sponging hsa-miR-646 and targeting NPM1
Survival: -
Supported No.:
 1
Description:

CircWHSC1 promotes endometrial cancer development through sponging miR-646 and targeting NPM1.
Other information
Title:

CircRNA WHSC1 targets the miR-646/NPM1 pathway to promote the development of endometrial cancer.

Journal: J Cell Mol Med
Published: 2020/5/8
PubMed ID: 32378344