circRNA basic information
circBase ID: -
Name: hsa_circ_CNOT6L
Synonym: -
Host Gene: hsa-miR-384
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: One normal cell line (HET-1A), ESCC cell lines (TE1, SKGT4)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FN1
Associated microRNA: hsa-miR-384
Biological function: CircCNOT6L knockdown attenuated ESCC cell proliferation and iron metabolism disorder, as well as accelerated apoptosis
Molecular mechanism: modulating hsa-miR-384/FN1 axis
Survival: -
Supported No.:
 3
Description:

circCNOT6L positively regulated the development of ESCC cells via modulating miR-384/FN1 axis. Our findings provided a theoretical basis for the therapy of ESCC patients.
Other information
Title:

Circular RNA circCNOT6L regulates cell development through modulating miR-384/FN1 axis in esophageal squamous cell carcinoma.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/4/25
PubMed ID: 32329843