circRNA basic information
circBase ID: -
Name: hsa_circ_PSMC3
Synonym: -
Host Gene: hsa-miR-296-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: OA chondrocytes
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-296-5p
Biological function: inhibits the proliferation and differentiation
Molecular mechanism: targeting miRNA-296-5p
Survival: -
Supported No.:
 1
Description:

CircPSM3 was upregulated in OA chondrocytes. CircPSM3 participated in the proliferation and differentiation of OA chondrocytes through targeted binding to miRNA-296-5p. CircPSM3 may become a potential therapeutic target for osteoarthritis treatment.
Other information
Title:

CircPSM3 inhibits the proliferation and differentiation of OA chondrocytes by targeting miRNA-296-5p.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/4/25
PubMed ID: 32329819