circRNA basic information
circBase ID: hsa_circ_0002770
Name: -
Synonym: circ_0002770
Host Gene: hsa-miR-331-3p
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: cell line
Sample type details: normal human epidermal melanocytes (NHEM), melanoma cell lines (SKMEL1, A375, A875)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: DUSP5 and TGFBR1
Associated microRNA: hsa-miR-331-3p
Biological function: promotes proliferation and invasion
Molecular mechanism: targeting hsa-miR-331-3p
Survival: poor
Supported No.:
 1
Description:

circ_0002770 facilitated melanoma cell proliferation, invasion and migration by sponging miR-331-3p and modulating DUSP5 and TGFBR1.
Other information
Title:

Circ_0002770, acting as a competitive endogenous RNA, promotes proliferation and invasion by targeting miR-331-3p in melanoma.

Journal: Cell Death Dis
Published: 2020/4/25
PubMed ID: 32327630