circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-193a-5p
 
 
 
Disease basic information
DO ID:
 2913
DO name: acute pancreatitis
Disease details: acute pancreatitis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: rat pancreatic acinar cells (AR42J)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GSDMD
Associated microRNA: hsa-miR-193a-5p
Biological function: Promotes Pyroptosis
Molecular mechanism: Through Regulation of the hsa-miR-193a-5p/GSDMD Axis
Survival: -
Supported No.:
 1
Description:

circHIPK3 promotes pyroptosis in acinar cells through regulation of the miR-193a-5p/GSDMD axis, which eventually aggravates AP disease.
Other information
Title:

CircHIPK3 Promotes Pyroptosis in Acinar Cells Through Regulation of the miR-193a-5p/GSDMD Axis.

Journal: Front Med (Lausanne)
Published: 2020/4/23
PubMed ID: 32318575