circRNA basic information
circBase ID: -
Name: hsa_circ_RGNEF
Synonym: -
Host Gene: hsa-miR-548
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SV-HUC, BC (J82, EJ, T24, TCC, UM-UC-3, RT-4) cell lines
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KIF2C
Associated microRNA: hsa-miR-548
Biological function: promote BC cell migration, proliferation, and invasion
Molecular mechanism: functioning as a hsa-miR-548 sponge to enhance KIF2C expression
Survival: -
Supported No.:
 1
Description:

circRGNEF suppresses BC progression by functioning as a miR-548 sponge to enhance KIF2C expression. Therefore, circRGNEF might be a candidate BC treatment target.
Other information
Title:

Circular RNA circRGNEF promotes bladder cancer progression via miR-548/KIF2C axis regulation.

Journal: Aging (Albany NY)
Published: 2020/4/20
PubMed ID: 32305958