circRNA basic information
circBase ID: -
Name: hsa_circ_CHFR
Synonym: -
Host Gene: hsa-miR-214-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human vascular smooth muscle cells (VSMCs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Wnt3/beta-catenin signals
Associated microRNA: hsa-miR-214-3p
Biological function: expedites cell growth, migration and inflammation in ox-LDL-treated human vascular smooth muscle cells
Molecular mechanism: via the hsa-miR-214-3p/Wnt3/beta-catenin pathway
Survival: -
Supported No.:
 6
Description:

Circ_CHFR contributed to the progression of AS through the miR-214-3p/Wnt3/beta-catenin signals, which illuminated the molecular mechanism of AS and suggested circ_CHFR might be an index for AS treatment.
Other information
Title:

Circ_CHFR expedites cell growth, migration and inflammation in ox-LDL-treated human vascular smooth muscle cells via the miR-214-3p/Wnt3/beta-catenin pathway.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/4/10
PubMed ID: 32271446