circRNA basic information
circBase ID: hsa_circ_0007534
Name: hsa_circ_DDX42
Synonym: -
Host Gene: hsa-miR-613
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Normal human colon mucosal epithelial cell line (NCM460), two CRC cell lines (LoVo, SW620)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC25A22
Associated microRNA: hsa-miR-613
Biological function: Circ_0007534 knockdown repressed CRC cell proliferation, colony formation, migration, invasion, and glycolysis
Molecular mechanism: regulating hsa-miR-613/SLC25A22 axis
Survival: -
Supported No.:
 3
Description:

We demonstrated that circ_0007534 knockdown suppressed the growth of CRC cells by regulating miR-613/SLC25A22 axis, providing potential target for the treatment of CRC.
Other information
Title:

Hsa_circ_0007534 knockdown represses the development of colorectal cancer cells through regulating miR-613/SLC25A22 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/4/10
PubMed ID: 32271418