circRNA basic information
circBase ID: -
Name: hsa_circ_FNDC3B
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CC cell lines (DLD1, HCT116, SW480, LoVo, Caco2, HT29), normal colon mucosal epithelial cell line (NCM460)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: Snail, FBP1
Associated microRNA: -
Biological function: inhibited the proliferation, invasion and migration of CC cells
Molecular mechanism: inhibited the expression of Snail, and subsequently promoted the tumor-suppressive effect of FBP1 in CC
Survival: -
Supported No.:
 1
Description:

circFNDC3B-218aa inhibited the expression of Snail, and subsequently promoted the tumor-suppressive effect of FBP1 in CC.
Other information
Title:

A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer.

Journal: Mol Cancer
Published: 2020/4/4
PubMed ID: 32241279