circRNA basic information
circBase ID: -
Name: hsa_circ_FOXK2
Synonym: -
Host Gene: hsa-miR-942
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PDAC cell lines (PANC1, SW1990, CAPAN-2, CFPAC1, BxPC-3, HEK293)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ANK1, GDNF, and PAX6
Associated microRNA: hsa-miR-942
Biological function: promoted cell growth, migration, and invasion and was involved in cell-cycle progression and apoptosis
Molecular mechanism: functioning as a sponge for hsa-miR-942, which in turn promoted expression of ANK1, GDNF, and PAX6
Survival: -
Supported No.:
 1
Description:

circFOXK2 promoted cell growth, migration, and invasion and was involved in cell-cycle progression and apoptosis. circFOXK2 contained multiple miRNA binding sites, functioning as a sponge for miR-942, which in turn promoted expression of ANK1, GDNF, and PAX6.

Other information
Title:

CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA-Binding Proteins and Sponging MiR-942.

Journal: Cancer Res
Published: 2020/3/29
PubMed ID: 32217695