circRNA basic information
circBase ID: -
Name: hsa_circ_EHMT1
Synonym: -
Host Gene: hsa-miR-1233-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human breast cancer cell lines (ZR-75-1, MCF-7, MB-468, T47D, SK-BR-3, MDA-MB-231, BT-549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: KLF4/MMP2
Associated microRNA: hsa-miR-1233-3p
Biological function: inhibits metastatic potential of breast cancer cells
Molecular mechanism: modulating hsa-miR-1233-3p/KLF4/MMP2 axis
Survival: -
Supported No.:
 1
Description:

circEHMT1 has potential as a prognostic factor in breast cancer and played a tumor suppressor role via the circEHMT1/miR-1233-3p/KLF4/MMP2 axis.
Other information
Title:

CircEHMT1 inhibits metastatic potential of breast cancer cells by modulating miR-1233-3p/KLF4/MMP2 axis.

Journal: Biochem Biophys Res Commun
Published: 2020/3/27
PubMed ID: 32209259