circRNA basic information
circBase ID: hsa_circ_0001971
Name: -
Synonym: circ_0001971
Host Gene: hsa-miR-194, hsa-miR-204
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: OSCC cell lines (CAL-27, SCC9), human oral keratinocytes (HOK)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-194, hsa-miR-204
Biological function: promote cell proliferation, migration, and invasion but suppress cisplatin (DDP) sensitivity and cell apoptosis
Molecular mechanism: interacting with hsa-miR-194 and hsa-miR-204
Survival: -
Supported No.:
 3
Description:

Circ_0001971 regulates cell proliferation, migration, invasion, apoptosis, and chemosensitivity of OSCC by interacting with miR-194 and miR-204 in vitro and in vivo. We provided a theoretical basis for the action mechanism of circ_0001971 on OSCC progression and chemosensitivity.
Other information
Title:

Circ_0001971 regulates oral squamous cell carcinoma progression and chemosensitivity by targeting miR-194/miR-204 in vitro and in vivo.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/3/21
PubMed ID: 32196598