circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human fetal bladder tissue cell line (CCC-HB-2), human bladder epithelial immortalized cell line (SV-HUC-1), BC cell lines (T24, J82, UMUC3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Promotes Gemcitabine Sensitivity
Molecular mechanism: -
Survival: better
Supported No.:
 4
Description:

The circHIPK3 is low-expressed in BC and is an independent prognostic biomarker for BC patients. The low-expression of circHIPK3 is associated with the insensitivity to gemcitabine of BC patients, over-expression of circHIPK3 promotes gemcitabine sensitivity in BC.
Other information
Title:

Circular RNA CircHIPK3 Promotes Gemcitabine Sensitivity in Bladder Cancer.

Journal: J Cancer
Published: 2020/3/21
PubMed ID: 32194801