circRNA basic information
circBase ID: hsa_circ_0038467
Name: hsa_circ_UQCRC2
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 552
DO name: pneumonia
Disease details: pneumonia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: 16HBE
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-338-3p
Biological function: regulates lipopolysaccharide-induced inflammatory injury
Molecular mechanism: sponging hsa-miR-338-3p
Survival: -
Supported No.:
 4
Description:

The current work had led to the identification of circ_0038467 knockdown that alleviated LPS-induced inflammatory injury in 16HBE cells at least partly through sponging miR-338-3p and regulating JAK/STAT3 pathway, highlighting novel molecular targets for the treatment of pneumonia.
Other information
Title:

Circ_0038467 regulates lipopolysaccharide-induced inflammatory injury in human bronchial epithelial cells through sponging miR-338-3p.

Journal: Thorac Cancer
Published: 2020/3/18
PubMed ID: 32181994