circRNA basic information
circBase ID: hsa_circ_0001105
Name: hsa_circ_SP140
Synonym: -
Host Gene: hsa-miR-766
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MG63, U2OS, 143b
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: YTHDF2
Associated microRNA: hsa-miR-766
Biological function: Inhibits Progression and Metastasis
Molecular mechanism: Sponging hsa-miR-766 and Activating YTHDF2 Expression
Survival: better
Supported No.:
 1
Description:

Our findings suggest that circ_0001105 inhibits OS progression, at least partially, by regulating miR-766/YTHDF2 signaling pathway.
Other information
Title:

Circular RNA circ_0001105 Inhibits Progression and Metastasis of Osteosarcoma by Sponging miR-766 and Activating YTHDF2 Expression.

Journal: Onco Targets Ther
Published: 2020/3/13
PubMed ID: 32161468